Prostate cancer is common in men over 50 years of age, with the risk of developing prostate cancer increasing with aging. Men with a first-degree relative, diagnosed with prostate cancer at a younger age will have an increased risk of developing the disease. The exact causes of prostate cancer are not known. Prostate cancer is comprised nearly always of adenocarcinoma cells that arise from glandular tissue. Prostate cancer commonly spreads to lymph nodes in the pelvis (metastasis to lymph nodes) and to the bones (metastasis to bones).


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Prostate Cancer Treatment In Malaysia


Symptoms & Signs

A patient with early prostate cancer is usually asymptomatic. Prostate cancer symptoms associated with enlargement of the prostate gland may include:

  • Frequent urination
  • Difficulty in starting or stopping the urine stream
  • A weak or interrupted urine stream
  • Urinary retention
  • Loss of control of urination
  • Painful urination
  • Blood in the urine or in the semen

Advanced prostate cancer symptoms may include:

  • Bone pain and bone fracture from minor trauma
  • Unexplained weight loss
  • Fatigue
  • Shortness of breath
  • Swelling of the legs related to obstruction of the lymph tissue by prostate cancer.

Screening and Diagnosis of Prostate Cancer

Talk to our oncologists at Onco Life Centre about when screening should begin based on your age and family history of the disease.

Prostate cancer screening consists of periodic laboratory testing, usually every one to two years, which includes a prostate specific antigen (PSA) test and digital rectal examination. However, the PSA is not sensitive enough to pick up all prostate cancers, and can also be raised even in people with prostate glands that are infected, inflamed, or enlarged but not cancerous.

An abnormal PSA and/or abnormal digital rectal examination are the indications for prostate biopsy. Prostate cancer is definitively diagnosed by removal of small cores of prostate tissue, which are then examined under the microscope by a pathologist. The prostate cancer present will be assigned a numerical score, which is referred to as the Gleason Score. This characterizes the appearance of the cancer cells and helps predict its likely level of aggressiveness.

The PSA level, Gleason score and the extent of involvement of the biopsy core will allow our prostate cancer specialists at Onco Life Centre to formulate the best multidisciplinary treatment plan for you.

Stages of prostate cancer

Clinical staging of prostate cancer is based on the pathology results, physical examination, PSA and radiologic studies. The American Joint Commission on Cancer (AJCC) TNM system for prostate cancer staging is as follows:


Prostate cancers cannot be seen on imaging tests or felt on examination.


Prostate cancers can be felt on examination and can be visualized with on imaging studies.


Prostate cancers have extended beyond the prostate gland to possibly involve the seminal vesicle or bladder neck.


Prostate cancers have invaded adjacent tissues or organs.


Means that there is no prostate cancer evident in the nearby nodes.


Means that there is evidence of prostate cancer in the nearby nodes.


Means that there is no evidence of spread of prostate cancer into distant tissues or organs.


Means that there is spread of prostate cancer into distant lymph nodes or organs.

The PSA and Gleason score at presentation as well as the final cancer stage designation determine the prognosis of the affected individuals.


prostate cancer Treatment options

Talk to our prostate cancer oncologists at Onco Life Centre about your treatment options. The main treatments for prostate cancer are surgery, hormonal therapy, chemotherapy and radiation therapy. Often the best approach uses 2 or more of these treatment methods. It is important that you understand the goal of your treatment. If a cure is not possible, treatment is aimed at relieving symptoms such as pain.

Surgery for prostate cancer

The removal of the entire prostate gland and the urethra that runs through the prostate and the attached seminal vesicles is referred to as a radical prostatectomy. Radical prostatectomy is an appropriate treatment option for men with clinically localized prostate cancer with a life expectancy of 10 or more years. Pelvic lymph node dissection may be recommended depending on the Gleason score, PSA, and radiologic findings.

Hormonal therapy for prostate cancer

Prostate cancer is highly sensitive to and dependent on the level of the male hormone testosterone, which drives the growth of prostate cancer cells, except in poorly differentiated forms of prostate cancer. Read More ...

Chemotherapy for prostate cancer

The use of chemotherapy in metastatic prostate cancer (Stage 4 prostate cancer) is able to relieve symptoms of prostate cancer, and can prolong life. It is usually used in the setting of castration-resistant prostate cancer. Read More ...

Targeted therapy for prostate cancer

There have been advances in the development of targeted therapy drugs for prostate cancer. If there is a BRCA mutation in the patient, then a PARP Inhibitor drug can be used to block PARP proteins, and make it very hard for the tumor cells with an abnrmal BRCA gene to repair damaged DNA, leading to the death of these cells. Our oncologist specialising in prostate cancer treatment prescribes this PARP inhibitor targeted therapy as an oral drug taken as a pill by mouth. It can be used in combination with hormonal therapy. Read More ...

Immunotherapy for prostate cancer

In immunoterapy for localized or metastatic prostate cancer, immune checkpoint inhibitors are used for patients whose prostate cancer cells have tested positive for specific gene changes. PD-1 inhibitor targets PD-1, a checkpoint protein on immune system cells called T cells, that normally helps keep these cells from attacking normal cells in the body. By blocking PD-1, this drug boosts the immune response against prostate cancer cells. It has shown promising results in prostate cancer treatment.

Please click here to learn more about Immunotherapy
Radiation therapy for prostate cancer

Radiation therapy is a potentially curative treatment that uses radiation to kill cancer cells. External beam therapy (EBRT) is appropriate for men who are candidates for radical prostatectomy but do not wish to undergo the surgery or who are not ideal surgical candidates. Read More ...

Bone-targeted therapy

Several bone-targeted therapies have been approved for use by the US FDA, as both prostate cancer as well ADT can have a significant impact on bone health. Read More ...



Risk Factors

Sixty percent of prostate cancer cases arise in men over 65 years of age.
Family history
Men with a first-degree relative, father or brother, diagnosed with prostate cancer at a younger age will have an increased risk of developing the disease. The risk of developing prostate cancer also increases with the number of relatives affected.
Genetic factors
Prostate cancer is, infrequently, directly attributed to identifiable genetic changes in the BRCA2 gene. BRCA2 gene mutation may increase risk of developing breast or ovarian cancer in affected female family members.
Lifestyle factors
Diets high in red meats and fatty foods and low in fruits and vegetables appear to be associated with a higher risk of developing prostate cancer. Obesity is also linked to a higher risk of the disease.


Our Best Prostate Cancer Oncologist

Onco Life Centre combines key elements of prostate cancer care and prostate cancer treatment under one roof, with convenience and speed. At Onco Life Centre, we have the necessary medical disciplines to achieve this. Our board certified highly experienced consultant oncologists have earned recognition for excellence in the field of prostate cancer treatment, providing our patients with the most advanced prostate cancer treatment options.


Dr. Christina Ng is a Consultant Medical Oncologist and Founder President of Empowered, The Cancer Advocacy Society of Malaysia.…


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Cost of prostate cancer treatment

Treatment cost for prostate cancer depends on several factors, such as the staging of the prostate cancer. Generally, using only chemotherapy is cheaper compared to using targeted therapy or immunotherapy. The more advanced the cancer stage, the more expensive it becomes to treat the cancer. At Onco Life Centre, the cost for treating prostate cancer using chemotherapy for most of our patients is around MYR4,000 per cycle. Adding in Targeted Therapy can go up from MYR8,000, depending on the specific type of targeted therapy drug used. Immunotherapy can range from MYR10,000 and above depending on the specific type and dosage of immunotherapy drug used.


Patients and their families have opportunities to talk about the way they are feeling with our oncologists, nurses, counselors, or join our psychosocial program and support group at Onco Life Centre.


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