Kidney cancer begins when healthy cells in 1 or both kidneys change and grow out of control, forming a mass called a renal cortical tumor.


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Kidney Cancer Treatment In Malaysia


Types of kidney cancer

There are several types of kidney cancer:

Renal cell carcinoma

Renal cell carcinoma (also commonly known as renal cancer or renal cell cancer) is the most common type of adult kidney cancer, making up about 85% of diagnoses.

Transitional cell carcinoma

This is also called urothelial carcinoma. It accounts for 10% to 15% of the kidney cancers diagnosed in adults.


Sarcoma of the kidney is rare and develops from the soft tissue of the kidney or the capsule or surrounding fat.

Wilms tumor

This is most common in children and is treated differently than kidney cancer in adults.


Lymphoma is associated with enlarged lymph nodes in other parts of the body, including the neck, chest, and abdominal cavity. In rare cases, kidney lymphoma can appear as a lone tumor mass in the kidney and may include enlarged regional lymph nodes.


Types of kidney cancer cell

The most common types of kidney cancer cells are listed below:

Clear cell

About 70% of kidney cancers are made up of clear cells. Clear cells range from slow growing to fast growing. Clear cell kidney cancer is particularly responsive to immunotherapy and targeted therapy.


Papillary kidney cancer develops in 10% to 15% of patients.

Sarcomatoid features

Each of the tumor subtypes of clear cell, chromophobe, and papillary in kidney cancer can show highly disorganized features under the microscope, also described as sarcomatoid which suggest a very aggressive form of kidney cancer.

Medullary/collecting duct

This is a rare and highly aggressive cancer that is more common in black people and is highly associated with having the sickle cell trait.


Chromophobe is uncommon and may form indolent tumors.


This is a slow-growing type of kidney cancer that rarely, if ever, spreads.



Our kidney cancer experts at Onco Life Centre can discuss your treatment options and recommendations based on several factors, including staging, the type, cell type, and stage of cancer, patient preferences and overall health.

Treatment for kidney cancer is most often with surgery, targeted therapy, immunotherapy, or a combination of these. Occasionally, radiation therapy and chemotherapy regimens for renal cell carcinoma are also used. Patients with kidney cancer that has spread (metastatic kidney cancer) often receive multiple lines of treatments.


Surgery for kidney cancer

If the cancer has not spread beyond the kidneys, surgery to remove the tumor, part or all of the kidney, and possibly nearby tissue and lymph nodes, may be the only treatment necessary. The types of surgery used for kidney cancer include the following procedures. Read More ...

Targeted therapy for kidney cancer

Targeted therapy for renal cell carcinoma (RCC) is a treatment that targets the cancer’s specific genes, proteins, or the tissue environment that contributes to cancer growth and survival. This type of treatment blocks the growth and spread of cancer cells while limiting damage to healthy cells. Read More ...

Immunotherapy for kidney cancer

Immunotherapy for renal cell carcinoma (RCC), is designed to boost the body’s natural defenses to fight cancer. It uses materials made either by the body or in a laboratory to improve, target, or restore immune system function. Read More ...

Chemotherapy for kidney cancer

Chemotherapy for renal cell carcinoma is the use of drugs to destroy cancer cells, usually by stopping the cancer cells ability to grow and divide. Read More ...

Radiation Therapy for kidney cancer

Radiation therapy is the use of high-energy x-rays to destroy cancer cells. Most often, radiation therapy is used when the cancer has spread to help ease symptoms, such as bone pain or swelling in the brain. The most common type of radiation treatment is called external-beam radiation therapy. When radiation treatment is given using implants, it is called internal radiation therapy or brachytherapy. Another type of radiation therapy is stereotactic radiosurgery, which is designed to direct the radiation therapy to a specific area without damaging nearby tissue.




Kidney cancer: Risk factors and prevention

The following factors may raise a persons risk of developing kidney cancer.

Smoking is believed to cause about 30% of kidney cancers in men and about 25% in women.
Exposure to cadmium
Some studies have shown a connection between exposure to the metallic element cadmium and kidney cancer.
Men are 2 to 3 times more likely to develop kidney cancer than women.
Chronic kidney disease
People who have decreased kidney function but dont yet need dialysis may be at higher risk for the development of kidney cancer.
Black people have higher rates of kidney cancer.
Long-term dialysis
People who have been on dialysis for a long time may develop cancerous cysts in their kidneys.
Kidney cancer is typically diagnosed between the ages of 50 and 70.
Family history of kidney cancer
People who have first-degree relatives, such as parents, brothers, sisters, or children, with kidney cancer have an increased risk of developing the disease. This risk increases if a number of extended family members have been diagnosed with kidney cancer, including grandparents, aunts, uncles, nieces, nephews, grandchildren, and cousins, and if these family members were diagnosed before the age of 50, had cancer in both kidneys, and/or had more than 1 tumor in the same kidney.
Nutrition and weight
Research has often shown a link between kidney cancer and obesity.
High blood pressure
Men with high blood pressure, also called hypertension, may be more likely to develop kidney cancer.
Inherited kidney cancer
Although kidney cancer can run in families, inherited kidney cancers are uncommon, occurring about 5% of the time. Finding a specific genetic syndrome in a family through genetic testing can help our oncologists at Onco Life Centre devise an appropriate cancer screening plan and, in some cases, help determine the best treatment options. Genetic conditions that increase a persons risk of developing kidney cancer include Von Hippel-Lindau syndrome, Hereditary non-VHL clear cell renal cell carcinoma, Hereditary papillary renal cell carcinoma, Birt-Hogg-Dub syndrome, Hereditary leiomyomatosis and renal cell carcinoma.


Our Best Kidney Cancer Oncologist

Onco Life Centre combines key elements of kidney cancer care and kidney cancer treatment under one roof, with convenience and speed. At Onco Life Centre, we have the necessary medical disciplines to achieve this. Our board certified highly experienced consultant oncologists have earned recognition for excellence in the field of kidney cancer treatment, providing our patients with the most advanced kidney cancer treatment options.


Dr. Christina Ng is a Consultant Medical Oncologist and Founder President of Empowered, The Cancer Advocacy Society of Malaysia.…


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Cost of kidney cancer treatment

Treatment cost for kidney cancer depends on several factors, such as the staging and the type of the kidney cancer. The more advanced the cancer stage, the more expensive it becomes to treat the cancer. At Onco Life Centre, the cost for treating kidney cancer using targeted therapy for most of our patients is about MYR5,000 per cycle. The cost of kidney cancer immunotherapy can range from MYR10,000 and above depending on the specific type and dosage of immunotherapy drug used.


Patients and their families have opportunities to talk about the way they are feeling with our oncologists, nurses, counselors, or join our psychosocial program and support group at Onco Life Centre.


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