Cancers are able to develop protective shields, thus rendering our body immune system unable to recognize and fight cancer cells. Cancer immunotherapy breaks down these shields and trains our body own defenses to find and destroy cancer cells.
Antigens are toxins or foreign substances that trigger an immune response, especially in the production of antibodies. Antigens are targeted by antibodies. Each antibody is specifically produced by the immune system to precisely match an antigen, and this leads to the initiation of a tailored immune response.
Immune checkpoints are regulators of the immune system. These pathways prevent the immune system from attacking your own healthy cells indiscriminately. However, cancer can find ways to hide from the immune system by activating these immune checkpoint targets. Checkpoint inhibitor is a form of immunotherapy that can block inhibitory checkpoints, which will amplify your body’s immune system to help destroy cancer cells. Common checkpoints that these inhibitors affect are the PD-1/PD-L1 and CTLA-4 pathways. Immunotherapy treatments can be used as a monotherapy or in combination with other cancer treatments.
The U.S. Food and Drug Administration (FDA) has approved many checkpoint inhibitors for specific cancers. At Onco Life Centre, our oncologists will specifically design your treatment plan, using such latest breakthroughs in cancer therapy.